By American Academy of Ophthalmology, Robert H. Rosa Jr. MD
Part four offers fabrics in elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: scientific features. half I makes use of a hierarchy that strikes from normal to express to assist derive a differential prognosis for a particular tissue. half II is a compilation of chosen scientific points of value to the overall ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging kinds for ocular and adnexal tumors.
Upon finishing touch of part four, readers will be capable to:
Describe a based method of knowing significant ocular stipulations in keeping with a hierarchical framework of topography, disorder approach, normal prognosis and differential diagnosis
Summarize the stairs in dealing with ocular specimens for pathologic examine, together with acquiring, dissecting, processing, and marking tissues
Identify these ophthalmic lesions that point out systemic ailment and are in all probability lifestyles threatening
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Additional info for 2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors
The iris diaphragm may be lost completely through a relatively small limbal rupture associated with 360° iridodialysis. A Vossius ring appears when compression and rupture of iris pigment epithelial cells against the anterior surface of the lens occur, depositing a ring of melanin pigment concentric to the pupil. A cataract may form immediately if the lens capsule is ruptured. The lens capsule is thinnest at the posterior pole, a point farthest away from the lens epithelial cells. The epithelium of the lens may be stimulated by trauma to form an anterior lenticular fibrous plaque.
4, Fibroblast activity and collagen and matrix deposition continue . The endothelium , sealing the inner wound, lays down new Descemet membrane. 5, Epithelial regeneration is complete. Fibroblasts fill the wound with type I collagen and repair slows. 6, The final wound contracts. The collagen fibers are not parallel with the surrounding lamellae. The number of fibroblasts decreases . l • 16 • Ophthalmic Patholqgy and lntraocular Tumors . healing. The endothelial cell adjacent to the wound lide across the posterior cornea; a few cells are replaced through mitotic activity.
A, Traction of the vitreous base on the peripheral retina (arrow) and ciliary body epithelium (asterisks) . B, Incorporation of peripheral retinal (arrow) and ciliary body tissue (arrowheads) into the vitreous base. C, Condensed vitreous base (asterisk), adherent retina (arrow), and RPE hyperplasia (arrowhead). (Courtesv of Hans E. ) 22 • Ophthalmic Pathology and lntraocular Tumors , A . B Figure 2-10 Focal posttraumatic choroidal granulomatous inflammation. A, Enucleated eye with a projectile causing a perforating limbal injury that extends to the posterior choroid .
2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors by American Academy of Ophthalmology, Robert H. Rosa Jr. MD