Download PDF by Anna Sienko: Advances in Surgical Pathology: Endometrial Carcinoma

By Anna Sienko

ISBN-10: 1609131789

ISBN-13: 9781609131784

Part of the preferred Advances in Surgical Pathology sequence, this quantity is a concise, up to date evaluation of the pathological features of endometrial melanoma. It emphasizes the histologic correlation, scientific administration, and remedy of endometrial melanoma, and contours present and rising ideas within the box. The publication offers a source for the well timed updates in wisdom which are worthwhile for day-by-day perform, for present credentialing, and for the self-assessment modules for recertification (MOC).

A unfastened significant other website positive factors absolutely searchable textual content in addition to over one hundred thirty full-color images.

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Extra resources for Advances in Surgical Pathology: Endometrial Carcinoma

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In patients with complex endometrial hyperplasia with atypia, persistence of the lesion or progression to adenocarcinoma was seen in 14% and 29% of patients, respectively. In patients with simple hyperplasia with atypia, persistence of the lesion or progression to adenocarcinoma was seen in 23% and 8% of patients, respectively. In patients with simple endometrial hyperplasia without atypia, persistence of the lesion or progression to adenocarcinoma occurred in 19% and 1% of patients, respectively.

Diagnosis of Atypia Atypia of the endometrial epithelium lining the proliferating glands is characterized by nuclear enlargement, round rather than oval nuclei, irregular distribution of the chromatin, and a variable presence of conspicuous nucleoli4 (Figs. 3-6 and 3-7). While assessing the presence of atypia, several issues should be considered. Artifactual Changes Secondary to Variations in Tissue Fixation and Processing Variations in tissue fixation and processing can induce changes in the appearance of the nuclei, including alterations in the chromatin distribution and the presence of nucleoli.

Simple or complex hyperplastic papillary proliferation, papillary proliferation, or benign papillary change). In our practice, we use the term “complex hyperplastic papillary proliferation” for those cases displaying a complex architectural pattern. In addition, we include a comment in the report indicating that this process represents a form of complex endometrial hyperplasia with metaplastic changes. 3,5,9 28 Section II • Histopathology FIGURE 3-12: Simple hyperplastic papillary proliferation of the endometrium in an endometrial polyp.

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Advances in Surgical Pathology: Endometrial Carcinoma by Anna Sienko


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