Prasanthi Karna, Lily Yang (auth.), George G. Chen Dr, Paul's Apoptosis in Carcinogenesis and Chemotherapy: Apoptosis in PDF

By Prasanthi Karna, Lily Yang (auth.), George G. Chen Dr, Paul B.S. Lai Dr (eds.)

ISBN-10: 1402095961

ISBN-13: 9781402095962

ISBN-10: 140209597X

ISBN-13: 9781402095979

The goal of this publication is to supply info on apoptotic techniques concerned with significant neoplastic ailments and their translations into rising anti-cancer options. The e-book is split into 15 chapters, each one of to be able to be interested by one specific melanoma (breast, bladder, cervical, colorectal, esophageal, gastric, laryngeal, liver, lung, nasopharyngeal, pancreatic, prostate, thyroid, leukaemia and cutaneous malignant melanoma). a couple of demonstrated leaders within the box have seriously summarized the hot discoveries relating apoptosis in a specific melanoma and its power for anti-cancer remedy. The publication describes how the apoptosis performs a job within the particular carcinogen-induced mobile and molecular adjustments throughout the improvement of the melanoma, and severely discusses how the rising anti-cancer method might be outfitted by means of the usage of the categorical carcinogen-related apoptotic pathway. as a result, this e-book can be not just for laboratory-based molecular and phone biologists and biochemists in melanoma learn but in addition for scientific oncologists and people operating within the pharmaceutical and biotechnological industries.

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Additional info for Apoptosis in Carcinogenesis and Chemotherapy: Apoptosis in cancer

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Br J Cancer 79:1651–1656 Miyashita T, Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293–299 Morizane Y, Honda R, Fukami K, Yasuda H (2005) X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO. J Biochem 137: 125–132 Motadi LR, Misso NL, Dlamini Z, Bhoola KD (2007) Molecular genetics and mechanisms of apoptosis in carcinomas of the lung and pleura: therapeutic targets. Int Immunopharmacol 7:1934–1947 Mullauer L, Mosberger I, Grusch M, Rudas M, Chott A (2000) Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer.

Cancer Res 65:11469–11477 Eramo A, Ricci-Vitiani L, Zeuner A, Pallini R, Lotti F, Sette G, Pilozzi E, Larocca LM, Peschle C, De Maria R (2006) Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ 13:1238–1241 Farnie G, Clarke RB, Spence K, Pinnock N, Brennan K, Anderson NG, Bundred NJ (2007) Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst 99:616–627 Fujikawa K, Shiraki K, Sugimoto K, Ito T, Yamanaka T, Takase K, Nakano T (2000) Reduced expression of ICE/caspase1 and CPP32/caspase3 in human hepatocellular carcinoma.

Svatek et al. , 2006). In vivo, urinary soluble Fas was an independent predictor of bladder cancer presence and invasiveness 2 Anti-Cancer Strategy of TCC of Bladder 31 in patients with a past history of non-muscle-invasive disease. Urinary soluble Fas outperformed NMP22 for both bladder cancer detection and staging. These observations suggest that soluble Fas may play a role in the local immunosuppression in bladder cancer associated with tumor development, biologic aggressiveness, and/or progression.

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Apoptosis in Carcinogenesis and Chemotherapy: Apoptosis in cancer by Prasanthi Karna, Lily Yang (auth.), George G. Chen Dr, Paul B.S. Lai Dr (eds.)

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