Download e-book for iPad: Cell Cycle Checkpoints and Cancer by Mikhail V. Blagosklonny

By Mikhail V. Blagosklonny

ISBN-10: 1587060671

ISBN-13: 9781587060670

Phone Cycle Checkpoints and melanoma is set mechanisms of standard and melanoma cellphone biking, checkpoint regulate, and the hyperlink of mitogenic signalling and mobile cycle equipment. Checkpoint mechanisms from yeast to guy are addressed to permit a finished realizing of the phone cycle. functions to present and destiny anticancer cures are mentioned.

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Proc Natl Acad Sci USA 1998; 95:8211-8215. 53. Sigal NH, Dumont FJ. Cyclosporin A, FK-506, and rapamycin: Pharmacologic probes of lymphocyte signal transduction. Annu Rev Immunol 1992; 10:519-560. 54. M. Barinaga M. From bench top to bedside. Science 1997; 278:1036-1039. 55. McCubrey JA, Steelman LS, Moye PW, et al. Effects of deregulated Raf and MEK1 expression on the cytokine-dependency of hematopoietic cells. Adv Enzyme Regl 2000; 40:305-337. 56. Beltman J, McCormick F, Cook SJ. The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, and activates Jun N-terminal kinase.

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Nonneoplastic hematopoietic myeloproliferative syndrome induced by dysregulated multi-CSF (IL-3) expression. Blood 1989; 73:1487-1497. 13. Cockayne DA, Bodine DM, Cline A et al. Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. Blood 1994; 84:2699-2710. 14. Perkins A, Kongsuwan K, Visvader J et al. Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. Proc Natl Acad Sci USA 1993; 87:8398-8402.

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Cell Cycle Checkpoints and Cancer by Mikhail V. Blagosklonny

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