By Haim I. Bicher, John R. McLaren, Giuseppe M. Pigliucci
Hyperthermia as a secure and powerful melanoma remedy modality is swiftly evolving propelled by means of common study and scientific efforts all over the world. displays on Hyperthermia adventure at the moment are regular at Oncology conferences, as are congresses committed solely to the intertwined interactions among easy sciences and sufferer therapy that jointly are forming the constitution of a brand new clinical forte. Such used to be the XII foreign Symposium on medical Hyperthermia held in Rome, Italy, April 27 - 29, 1989. Papers provided therein represent the spine of this ebook. Biology examine has supplied info describing mechanisms of motion for the melanoma mobile killing and physiological results of Hyperthermia. Physics study has ended in the improvement of kit permitting remedy of many components of the human physique, in addition to defined the constraints that also constrain our skill to regard, specially within the parts of deep seated tumor heating and non-invasive thermometry. the most query that might make a decision the way forward for this modality is that of its medical use. to place it succinctly, what will we do with this very likely useful gizmo in a regular scientific oncological perform . •• ? this can be the most query addressed during this ebook as "Consensus on Hyperthermia for the Nineteen Nineties. " The publication in cludes 28 offered papers and 25 invited chapters from a number of the best specialists within the box. Their simple mechanisms of motion have been physics ideas, remedy caliber coverage and particularly, medical indications.
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Additional resources for Consensus on Hyperthermia for the 1990s: Clinical Practice in Cancer Treatment
18. : Mass Transfer in Tumors: Characterization and Applications in Chemotherapy. Adv. Cancer Res. 33:251-311, 1980. 19. : Regulation of Blood Circulation in Malignant Tumors. Vopr. Onkol. 5:14-23, 1959. 20. : A Histophatologic Study on the Effects of Radiofrequency Thermo Therapy on Malignant Tumors of the Lung. Cancer 43:767, 1979. 21. K. et al. Human Hyperthermic Therapy: Relationship Between Tumor Type and Capacity to Induce Hyperthermia by Radio Frequency. Am. J. Surg. 138:170-174, 1979b. 22.
Am. J. Clin. Oncol. 9: 162-169, 1986. 104) Steindorfer, P; Germann, R; Schneider, G ; et al : Our experience with an annular phased array hyperthermia system in the treatment of advanced recurrences of the pelvis. Strahlentherapie und Onkologie 163: 439-442, 1987. 105) KUbota, Y; Shu in, T ; Miura, T ; et al : Treatment of bladder cancer with a combination of hyperthermia, radiation and bleomycin. Cancer 53: 199-202, 1984. 106) Szmigielski, S; Zielinski, H; Stawarz, 8; et al : Local mlcrowave hyperthermia in treatment of advanced prostatic adenocarcinoma.
I. Bicher et 0/. Plenum Press, New York, 1990 47 1. Instrumentation a. We need equipment that will give uniform heat to any desired depth, similar to ionizing radiation. This could be achieved by use of ultrasound with different frequencies, either from a fixed source or a moveable source. b. Radio frequency or microwave by use of mUltiple applicators or moveable applicators. c. Combining regional or whole body hyperthermia with local hyperthermia for more uniform heat to the area. 2. Thermometry a.
Consensus on Hyperthermia for the 1990s: Clinical Practice in Cancer Treatment by Haim I. Bicher, John R. McLaren, Giuseppe M. Pigliucci